Redox-Reaction Based Spectrophotometric Assay of Isoniazid in Pharmaceuticals
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چکیده
منابع مشابه
Sensitive Spectrophotometric Assay of Isoniazid in Pharmaceuticals using Cerium(IV) and Two Acid Dyes
Two simple, rapid, selective and sensitive spectrophotometric methods are proposed for the assay of isoniazid (INH) in pure form and in tablets. The methods are based on the oxidation of INH by a measured excess of Ce(IV) in acid medium followed by determination of surplus oxidant by reacting with a fixed quantity of methyl orange (method A) or indigo carmine (method B) and measuring the absorb...
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Two sensitive spectrophotometric methods are described for the determination of lansoprazole (LPZ) in bulk drug and in capsule formulation. The methods are based on the oxidation of lansoprazole by insitu generated bromine followed by determination of unreacted bromine by two different reaction schemes. In one procedure (method A), the residual bromine is treated with excess of iron (II), and t...
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A novel simple kinetic spectrophotometric method for the determination of N-acetyl-L-cysteine (NAC) has been developed and validated. The proposed method is based on a coupled redox-complexation reaction, the first step of which is the reduction of Fe(3+) by NAC; the second one includes the complexation of Fe(2+), resulting from the preceding redox reaction, with 2,4,6-trypyridyl-s-triazine (TP...
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Background: Diethylcarbamazine citrate (DEC) is the drug of choice for the treatment of lymphatic filariasis, a disease which affects people in the tropical areas of the world. Mass treatment with DEC is recommended for control of lymphatic filariasis and in this connection, there is a need for an assay which could be used for the purpose of medication control. Objective: The present study is a...
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Titrimetric and spectrophotometric methods are described for the determination of oxcarbazepine (OXC) in bulk drug and in tablets. The methods use N-bromosuccinimide (NBS) and bromopyrogallol red (BPR) as reagents. In titrimetry (method A), an acidified solution of OXC is titrated directly with NBS using methyl orange as indicator. Spectrophotometry (method B) involves the addition of known exc...
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ژورنال
عنوان ژورنال: ISRN Analytical Chemistry
سال: 2014
ISSN: 2090-732X
DOI: 10.1155/2014/717019